This paper studies frame synchronization for use with the advanced communication link transmission unit format that was recently proposed for updating the telecommand synchronization and channel coding standard for space applications. With a view to improving the robustness against jamming, future satellite telecommand systems are planning to adopt direct-sequence spread spectrum modulation and advanced channel coding. Compared to the frame synchronization algorithm specified in the current Consultative Committee for Space Data Systems (CCSDS) recommendation, we consider a longer start sequence and relax the condition for declaring synchronization. We investigate the performance of this algorithm in the presence of jamming, and show that the frame synchronizer can be designed such that the overall system’s robustness against pulsed jamming is limited by the robustness of the code rather than the synchronizer.