The quantize-and-forward (QF) cooperative protocol can effectively be used to combat fading in systems using half-duplex relay terminals. While the outage behavior of the QF protocol has been extensively investigated, few research has been performed on the impact of imperfect channel estimates. In this contribution, a lower bound (LB) on the estimation error is obtained for a one-hop relaying channel with data quantization at the relay. To this purpose the modified Cramer-Rao (MCRB) bound is calculated, which, compared to the true Cramer-Rao bound (CRB), is a looser and computationally less complex bound that converges to the CRB in the high signal-to-noise ratios. By using a general system model for the relay channel, the obtained results can be utilized to benchmark a wide variety of systems.